Approaches

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EWAS

Environment/Exposome-wide association studies (EWAS) is an analytic approach, similar to Genome-wide association studies (GWAS), which is to identify the assoociation between exposures and disease/disease related traits (Patel. 2014). There are several advantages to perform EWAS: 1) This approach allows to search the environmental data at large scale and adjust them accordingly; 2) Results from EWAS are all the probed associatiions.

Fig 1. –log₁₀(pvalue) of association to type 2 diabetes mellitus for 253 biomarkers of environmental factors (Adapted from Patel CJ, et al. 2010 )

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